InthewakeofatrucebetweentheNiceSideandtheMiceSide,theZooversehassettledintoaneraofpeace.Thevillainousmouse,BooBooSqueal,isdeterminedtoviolatethatpeacetreaty,andrestartwaratanycost.NiceSideheroes,NukeandB-52,areforcedtofendforthemselves,thwartingBooBoo'svengefulminionsanddefendingtheZooversewitheverythingthey'vegotaaa